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    CG30059 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246425, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG30059provided by FlyBase
    Primary source
    FLYBASE:FBgn0260475
    Locus tag
    Dmel_CG30059
    See related
    AllianceGenome:FB:FBgn0260475
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.22; Dmel\CG30059
    Old locus tag
    CG30059
    Summary
    Predicted to enable N-acetylglucosamine-6-sulfatase activity. Predicted to be involved in glycosaminoglycan metabolic process. Is expressed in adult heart and organism. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    50A5-50A5; 2-68 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13412769..13414620, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9300274..9302125, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Baramicin A2 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Baramicin A1 Neighboring gene ATPase 8A Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Isoleucine-AAT 1-3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance. Nagy S, et al. PLoS Genet, 2018 Dec. PMID 30566533, Free PMC Article
    2. Activating transcription factor 3 regulates immune and metabolic homeostasis. Rynes J, et al. Mol Cell Biol, 2012 Oct. PMID 22851689, Free PMC Article
    3. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article
    4. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. Lunardi A, et al. Proc Natl Acad Sci U S A, 2010 Apr 6. PMID 20308539, Free PMC Article
    5. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables N-acetylglucosamine-6-sulfatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycosaminoglycan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30059-PA
    NP_610872.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13412769..13414620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137028.4 → NP_610872.1  uncharacterized protein Dmel_CG30059 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610872.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NX7, Q95R73
      Related
      FBpp0086832
      Conserved Domains (2) summary
      COG3119
      Location:24 → 464
      AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
      cd16147
      Location:24 → 467
      G6S; glucosamine (N-acetyl)-6-sulfatase(G6S, GNS) AND sulfatase 1(SULF1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95R73 Q95R73

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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