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    CG30043 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246412, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CG30043provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050043
    Locus tag
    Dmel_CG30043
    See related
    AllianceGenome:FB:FBgn0050043
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13161; Dmel\CG30043
    Summary
    Predicted to be involved in proteolysis. Is expressed in embryonic large intestine; garland cell primordium; organism; and plasmatocyte primordium. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG30043 in Genome Data Viewer
    Location:
    49A1-49A1; 2-67 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12359436..12363165)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8246941..8250670)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster. Sun W, et al. Insect Mol Biol, 2006 Aug. PMID 16907832
    2. Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. Erkosar B, et al. PLoS One, 2014. PMID 24733183, Free PMC Article
    3. Functional genomic analysis of the periodic transcriptome in the developing Drosophila wing. Liang L, et al. Dev Cell, 2014 Apr 14. PMID 24684830
    4. Genetic variation in food choice behaviour of amino acid-deprived Drosophila. Toshima N, et al. J Insect Physiol, 2014 Oct. PMID 25010547
    5. SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis. Chaplot K, et al. Dis Model Mech, 2019 Feb 7. PMID 30635270, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30043-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12359436..12363165
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165889.2 → NP_725143.1  uncharacterized protein Dmel_CG30043 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725143.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MKL0
      Related
      FBpp0087018
      Conserved Domains (2) summary
      cd03875
      Location:71 → 377
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
      cl21590
      Location:493 → 634
      PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MKL0 Q8MKL0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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