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    sulp-7 SLC26A/SulP transporter domain-containing protein;STAS domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189195, updated on 2-Nov-2024

    Summary

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    Official Symbol
    sulp-7
    Official Full Name
    SLC26A/SulP transporter domain-containing protein;STAS domain-containing protein
    Primary source
    WormBase:WBGene00012259
    Locus tag
    CELE_W04G3.6
    See related
    AllianceGenome:WB:WBGene00012259
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in body wall musculature; hypodermis; intestine; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); bone disease (multiple); calcium oxalate nephrolithiasis; and diarrhea (multiple). Orthologous to several human genes including SLC26A1 (solute carrier family 26 member 1); SLC26A2 (solute carrier family 26 member 2); and SLC26A3 (solute carrier family 26 member 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See sulp-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (11080678..11087474)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Phospholipase A(2) Neighboring gene Uncharacterized protein Neighboring gene Phospholipase A2 Neighboring gene ncRNA Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 2 Neighboring gene tRNA-Leu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The abts and sulp families of anion transporters from Caenorhabditis elegans. Sherman T, et al. Am J Physiol Cell Physiol, 2005 Aug. PMID 15814591
    2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables bicarbonate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chloride transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables monoatomic anion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxalate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in bicarbonate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in inorganic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in oxalate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sulfate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SLC26A/SulP transporter domain-containing protein;STAS domain-containing protein
    NP_001033568.1
    • Confirmed by transcript evidence
    NP_001033569.1
    • Confirmed by transcript evidence
    NP_001033570.1
    • Confirmed by transcript evidence
    NP_001033571.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      11080678..11087474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038482.4 → NP_001033571.1  STAS domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033571.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EC30
      Conserved Domains (1) summary
      TIGR00815
      Location:14 → 563
      sulP; high affinity sulphate transporter 1

    2. NM_001038481.4 → NP_001033570.1  SLC26A/SulP transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033570.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFX9
      Conserved Domains (1) summary
      pfam00916
      Location:28 → 272
      Sulfate_transp; Sulfate permease family

    3. NM_001038480.2 → NP_001033569.1  SLC26A/SulP transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033569.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EE27
      Conserved Domains (1) summary
      pfam00916
      Location:31 → 274
      Sulfate_transp; Sulfate permease family

    4. NM_001038479.2 → NP_001033568.1  SLC26A/SulP transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033568.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGG6
      Conserved Domains (1) summary
      pfam00916
      Location:11 → 254
      Sulfate_transp; Sulfate permease family
    Nucleotide Protein
    Heading Accession and Version

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