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    F49E12.10 Fatty acid hydroxylase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186061, updated on 18-Sep-2024

    Summary

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    Official Symbol
    F49E12.10
    Official Full Name
    Fatty acid hydroxylase domain-containing protein
    Primary source
    WormBase:WBGene00009903
    Locus tag
    CELE_F49E12.10
    See related
    AllianceGenome:WB:WBGene00009903
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human FAXDC2 (fatty acid hydroxylase domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See F49E12.10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (8391051..8392283)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Fatty acid hydroxylase domain-containing protein Neighboring gene Protein phosphatase inhibitor 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EXPERA domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables C-4 methylsterol oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sterol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fatty acid hydroxylase domain-containing protein
    NP_495764.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8391051..8392283
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063363.3 → NP_495764.1  Fatty acid hydroxylase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20612
      Conserved Domains (1) summary
      pfam04116
      Location:116 → 237
      FA_hydroxylase; Fatty acid hydroxylase superfamily
    Nucleotide Protein
    Heading Accession and Version

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