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    rgs-10 Regulator of G-protein signaling rgs-10 [ Caenorhabditis elegans ]

    Gene ID: 185764, updated on 28-Oct-2024

    Summary

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    Official Symbol
    rgs-10
    Official Full Name
    Regulator of G-protein signaling rgs-10
    Primary source
    WormBase:WBGene00004353
    Locus tag
    CELE_F45B8.2
    See related
    AllianceGenome:WB:WBGene00004353
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in negative regulation of signal transduction. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Orthologous to several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS16 (regulator of G protein signaling 16). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See rgs-10 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (14962756..14964143)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Intrinsically Disordered Protein, expressed in Pharynx Neighboring gene ncRNA Neighboring gene Regulator of G-protein signaling rgs-11 Neighboring gene Peptidase A2 domain-containing protein Neighboring gene ncRNA Neighboring gene PilS cassette

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed. Dong MQ, et al. Genes Dev, 2000 Aug 15. PMID 10950865, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Regulator of G-protein signaling rgs-10
    NP_510482.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14962756..14964143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078081.2 → NP_510482.1  Regulator of G-protein signaling rgs-10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510482.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45523
      Conserved Domains (1) summary
      pfam00615
      Location:135 → 251
      RGS; Regulator of G protein signaling domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O45523.1

    Gene LinkOut

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