U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    pcrg-1 [ Caenorhabditis elegans ]

    Gene ID: 184039, updated on 22-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pcrg-1
    Primary source
    WormBase:WBGene00017122
    Locus tag
    CELE_E04F6.2
    See related
    AllianceGenome:WB:WBGene00017122
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable Hsp70 protein binding activity; Hsp90 protein binding activity; and chaperone binding activity. Predicted to be involved in negative regulation of cell death. Is expressed in head neurons. Orthologous to several human genes including PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See pcrg-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (7200549..7201882)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MaoC-like domain-containing protein Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class D (Delta) Neighboring gene Serpentine Receptor, class D (delta)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis. Dawe HR, et al. J Cell Sci, 2005 Dec 1. PMID 16278296
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables Hsp90 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Parkin coregulated gene protein homolog
    NP_495496.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7200549..7201882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063095.4 → NP_495496.2  Parkin coregulated gene protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495496.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19060
      Conserved Domains (1) summary
      pfam10274
      Location:102 → 290
      ParcG; Parkin co-regulated protein
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools