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    sulp-3 [ Caenorhabditis elegans ]

    Gene ID: 181094, updated on 22-Aug-2024

    Summary

    Official Symbol
    sulp-3
    Primary source
    WormBase:WBGene00018283
    Locus tag
    CELE_F41D9.5
    See related
    AllianceGenome:WB:WBGene00018283
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable anion transmembrane transporter activity. Predicted to be involved in anion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in pm3; pm4; pm5; pm6; and pm7. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61; bone disease (multiple); calcium oxalate nephrolithiasis; and spermatogenic failure 3. Orthologous to several human genes including SLC26A1 (solute carrier family 26 member 1); SLC26A10 (solute carrier family 26 member 10); and SLC26A2 (solute carrier family 26 member 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (8403539..8408367, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Asn Neighboring gene ncRNA Neighboring gene tRNA-Leu

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables bicarbonate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chloride transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oxalate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in bicarbonate transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in oxalate transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sulfate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Sulfate permease family protein 3
    NP_509424.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8403539..8408367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077023.5NP_509424.2  Sulfate permease family protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509424.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q58G77, Q58QG5, Q94225
      Conserved Domains (2) summary
      pfam00916
      Location:60496
      Sulfate_transp; Sulfate permease family
      pfam01740
      Location:551696
      STAS; STAS domain