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    fask-1 RAP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178263, updated on 28-Oct-2024

    Summary

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    Official Symbol
    fask-1
    Official Full Name
    RAP domain-containing protein
    Primary source
    WormBase:WBGene00007207
    Locus tag
    CELE_B0564.7
    See related
    AllianceGenome:WB:WBGene00007207
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Orthologous to human TBRG4 (transforming growth factor beta regulator 4). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See fask-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (13100715..13104627)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Replication factor C subunit 3 Neighboring gene Dynein light intermediate chain Neighboring gene Putative exosome complex component RRP41 Neighboring gene Mitochondrial import inner membrane translocase subunit Tim10B Neighboring gene RNA interference defective protein 11 Neighboring gene Fe2OG dioxygenase domain-containing protein Neighboring gene Bestrophin homolog 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial RNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitochondrial mRNA stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ribonucleoprotein granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RAP domain-containing protein
    NP_001294013.1
    • Confirmed by transcript evidence
    NP_502521.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13100715..13104627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070120.6 → NP_502521.2  RAP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502521.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17532
      Conserved Domains (1) summary
      pfam06743
      Location:377 → 409
      FAST_1; FAST kinase-like protein, subdomain 1

    2. NM_001307084.3 → NP_001294013.1  RAP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294013.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AL82
      Conserved Domains (1) summary
      pfam02399
      Location:4 → 119
      Herpes_ori_bp; Origin of replication binding protein
    Nucleotide Protein
    Heading Accession and Version

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