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    his-61 Histone H2A [ Caenorhabditis elegans ]

    Gene ID: 177521, updated on 2-Nov-2024

    Summary

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    Official Symbol
    his-61
    Official Full Name
    Histone H2A
    Primary source
    WormBase:WBGene00001935
    Locus tag
    CELE_F55G1.10
    See related
    AllianceGenome:WB:WBGene00001935
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is expressed in germ line; intestine; nervous system; and somatic cell. Orthologous to several human genes including H2AX (H2A.X variant histone). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See his-61 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (7485834..7486217, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SLC (SoLute Carrier) homolog Neighboring gene Putative pyrroline-5-carboxylate reductase Neighboring gene Kinetochore-associated protein rod-1 Neighboring gene putative histone H2B 4 Neighboring gene Histone H4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B. Liu Y, et al. Structure, 2019 Dec 3. PMID 31653339
    2. Reference quantitative transcriptome dataset for adult Caenorhabditis elegans. Piovesan A, et al. Data Brief, 2019 Aug. PMID 31440537, Free PMC Article
    3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Histone H2A
    NP_501201.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7485834..7486217 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068800.5 → NP_501201.1  Histone H2A [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501201.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P09588, Q7JKF5
      Conserved Domains (1) summary
      PTZ00017
      Location:18 → 127
      PTZ00017; histone H2A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P09588.2

    Gene LinkOut

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