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    T12D8.10 BolA family protein [ Caenorhabditis elegans ]

    Gene ID: 176801, updated on 2-Nov-2024

    Summary

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    Official Symbol
    T12D8.10
    Official Full Name
    BolA family protein
    Primary source
    WormBase:WBGene00023450
    Locus tag
    CELE_T12D8.10
    See related
    AllianceGenome:WB:WBGene00023450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to be active in cytosol and nucleus. Orthologous to human BOLA2 (bolA family member 2) and BOLA2B (bolA family member 2B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See T12D8.10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (13641795..13642327, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Acyl-CoA-binding domain-containing protein 6 Neighboring gene Serine/arginine-rich splicing factor 2 Neighboring gene PHD-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein maturation by iron-sulfur cluster transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BolA family protein
    NP_001022757.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13641795..13642327 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027586.6 → NP_001022757.1  BolA family protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022757.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q69ZI6
      Conserved Domains (1) summary
      pfam01722
      Location:12 → 78
      BolA; BolA-like protein
    Nucleotide Protein
    Heading Accession and Version

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