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    lec-4 Galectin [ Caenorhabditis elegans ]

    Gene ID: 175488, updated on 2-Nov-2024

    Summary

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    Official Symbol
    lec-4
    Official Full Name
    Galectin
    Primary source
    WormBase:WBGene00002267
    Locus tag
    CELE_C44F1.3
    See related
    AllianceGenome:WB:WBGene00002267
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables galactoside binding activity. Located in membrane raft. Orthologous to human LGALS9 (galectin 9) and LGALS9B (galectin 9B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See lec-4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (3771425..3773326, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene SAND domain-containing protein Neighboring gene adenylate cyclase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reinforcement of frontal affinity chromatography for effective analysis of lectin-oligosaccharide interactions. Hirabayashi J, et al. J Chromatogr A, 2000 Aug 25. PMID 11009029
    2. Caenorhabditis elegans galectins LEC-1-LEC-11: structural features and sugar-binding properties. Nemoto-Sasaki Y, et al. Biochim Biophys Acta, 2008 Oct. PMID 18675319
    3. A Caenorhabditis elegans glycolipid-binding galectin functions in host defense against bacterial infection. Ideo H, et al. J Biol Chem, 2009 Sep 25. PMID 19635802, Free PMC Article
    4. A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large. Waaijers S, et al. BMC Biol, 2016 Aug 9. PMID 27506200, Free PMC Article
    5. An analysis of the Caenorhabditis elegans lipid raft proteome using geLC-MS/MS. Rao W, et al. J Proteomics, 2011 Feb 1. PMID 21070894

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables galactoside binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactoside binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane raft HDA PubMed 

    General protein information

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    Preferred Names
    Galectin
    NP_497763.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3771425..3773326 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065362.9 → NP_497763.1  Galectin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497763.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18625, Q9GNP5
      Conserved Domains (1) summary
      smart00276
      Location:14 → 145
      GLECT; Galectin
    Nucleotide Protein
    Heading Accession and Version

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