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    C05C10.2 DNA2/NAM7 helicase-like C-terminal domain-containing protein;putative ATP-dependent helicase C05C10.2 [ Caenorhabditis elegans ]

    Gene ID: 174546, updated on 2-Nov-2024

    Summary

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    Official Symbol
    C05C10.2
    Official Full Name
    DNA2/NAM7 helicase-like C-terminal domain-containing protein;putative ATP-dependent helicase C05C10.2
    Primary source
    WormBase:WBGene00007329
    Locus tag
    CELE_C05C10.2
    See related
    AllianceGenome:WB:WBGene00007329
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See C05C10.2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    11
    Sequence:
    Chromosome: II; NC_003280.10 (9922219..9930846)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene C6 domain-containing protein Neighboring gene Putative acid phosphatase 10 Neighboring gene Putative acid phosphatase 11 Neighboring gene putative succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA2/NAM7 helicase-like C-terminal domain-containing protein;putative ATP-dependent helicase C05C10.2
    NP_001364520.1
    • Partially confirmed by transcript evidence
    NP_001364521.1
    • Partially confirmed by transcript evidence
    NP_001364579.1
    • Confirmed by transcript evidence
    NP_001364625.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9922219..9930846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001377846.1 → NP_001364579.1  putative ATP-dependent helicase C05C10.2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09449
      Conserved Domains (2) summary
      COG1112
      Location:941 → 1442
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      cd18808
      Location:1253 → 1433
      SF1_C_Upf1; C-terminal helicase domain of Upf1-like family helicases

    2. NM_001377845.3 → NP_001364625.1  DNA2/NAM7 helicase-like C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZZ3
      Conserved Domains (2) summary
      COG1112
      Location:941 → 1442
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      cd18808
      Location:1253 → 1433
      SF1_C_Upf1; C-terminal helicase domain of Upf1-like family helicases

    3. NM_001377847.2 → NP_001364520.1  DNA2/NAM7 helicase-like C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9MPX1
      Conserved Domains (2) summary
      COG1112
      Location:820 → 1321
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      cd18808
      Location:1132 → 1312
      SF1_C_Upf1; C-terminal helicase domain of Upf1-like family helicases

    4. NM_001377848.3 → NP_001364521.1  DNA2/NAM7 helicase-like C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9MNI8
      Conserved Domains (2) summary
      COG1112
      Location:820 → 1321
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      cd18808
      Location:1132 → 1312
      SF1_C_Upf1; C-terminal helicase domain of Upf1-like family helicases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09449.2

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