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    ensa-1 [ Caenorhabditis elegans ]

    Gene ID: 172837, updated on 22-Aug-2024

    Summary

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    Official Symbol
    ensa-1
    Primary source
    WormBase:WBGene00010730
    Locus tag
    CELE_K10C3.2
    See related
    AllianceGenome:WB:WBGene00010730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human ARPP19 (cAMP regulated phosphoprotein 19) and ENSA (endosulfine alpha). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ensa-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (9850020..9851791, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Non-histone chromosomal protein HMG-14 Neighboring gene NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-62 Neighboring gene Zwei Ig domain protein zig-1 Neighboring gene ncRNA Neighboring gene Transmembrane protein 98 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans. Kim MY, et al. Genetics, 2012 Aug. PMID 22649080, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of protein dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mRNA stability protein
    NP_492609.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9850020..9851791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060208.7 → NP_492609.1  mRNA stability protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492609.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XU56
      Conserved Domains (1) summary
      pfam04667
      Location:16 → 81
      Endosulfine; cAMP-regulated phosphoprotein/endosulfine conserved region
    Nucleotide Protein
    Heading Accession and Version

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