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    CG43165 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 12798550, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CG43165provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262721
    Locus tag
    Dmel_CG43165
    See related
    AllianceGenome:FB:FBgn0262721
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG43165
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Orthologous to human EPPIN-WFDC6 (EPPIN-WFDC6 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG43165 in Genome Data Viewer
    Location:
    24B2-24B2; 2-10 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3694431..3695020, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3694431..3695020, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Accessory gland protein 24A4 Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Immune induced molecule 33

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    2. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
    3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    4. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article
    5. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG43165-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3694431..3695020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258929.2 → NP_001245858.1  uncharacterized protein Dmel_CG43165 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245858.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NDD9
      Conserved Domains (1) summary
      cl00101
      Location:24 → 81
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NDD9 M9NDD9

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