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    spi2 Spi-2 proto-oncogene [ Danio rerio (zebrafish) ]

    Gene ID: 103910445, updated on 2-Nov-2024

    Summary

    Official Symbol
    spi2provided by ZNC
    Official Full Name
    Spi-2 proto-oncogeneprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131121-377
    See related
    Ensembl:ENSDARG00000087438 AllianceGenome:ZFIN:ZDB-GENE-131121-377
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-257i7.5
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in caudal hematopoietic tissue; dorsal aorta; endothelial cell; and ventral wall of dorsal aorta. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See spi2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (17801500..17806129, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (17812610..17817145, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene choline phosphotransferase 1 Neighboring gene myosin binding protein C1 Neighboring gene Spi-C transcription factor (Spi-1/PU.1 related) Neighboring gene DnaJ heat shock protein family (Hsp40) member B9b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      17801500..17806129 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009300320.4XP_009298595.1  transcription factor Spi-C

      UniProtKB/TrEMBL
      A0A8M3ARG0
      Related
      ENSDARP00000108883.1, ENSDART00000128988.3
      Conserved Domains (1) summary
      pfam00178
      Location:121202
      Ets; Ets-domain