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    Armh3 armadillo-like helical domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 103689959, updated on 2-Nov-2024

    Summary

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    Symbol
    Armh3provided by RGD
    Full Name
    armadillo-like helical domain containing 3provided by RGD
    Primary source
    RGD:9299787
    See related
    EnsemblRapid:ENSRNOG00000025523 AllianceGenome:RGD:9299787
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    C1H10orf76; RGD1564887
    Summary
    Predicted to be involved in regulation of Golgi organization. Predicted to be located in Golgi membrane. Predicted to be active in cytosol. Orthologous to human ARMH3 (armadillo like helical domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 79.4), Adrenal (RPKM 76.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Armh3 in Genome Data Viewer
    Location:
    1q54
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (254615274..254797673, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (244666250..244848688, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (265574715..265757254, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene O-GlcNAcase Neighboring gene potassium voltage-gated channel interacting protein 2 Neighboring gene HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 Neighboring gene LIM domain binding 1 Neighboring gene LIM domain binding 1 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion. Chan CJ, et al. Mol Cell Proteomics, 2019 Nov. PMID 31519766, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of Golgi organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    armadillo-like helical domain-containing protein 3
    Names
    UPF0668 protein C10orf76 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402549.1 → NP_001389478.1  armadillo-like helical domain-containing protein 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZM80, A6JHK3
      Related
      ENSRNOP00000077077.2, ENSRNOT00000113407.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      254615274..254797673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039101424.2 → XP_038957352.1  armadillo-like helical domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A824, D3ZZE3
      Related
      ENSRNOP00000051587.5, ENSRNOT00000054703.7
      Conserved Domains (1) summary
      pfam08427
      Location:422 → 650
      DUF1741; Domain of unknown function (DUF1741)

    2. XM_017590384.3 → XP_017445873.1  armadillo-like helical domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A824
      Related
      ENSRNOP00000079077.2, ENSRNOT00000108107.2

    3. XM_039101426.2 → XP_038957354.1  armadillo-like helical domain-containing protein 3 isoform X4

      Conserved Domains (1) summary
      pfam08427
      Location:161 → 389
      DUF1741; Domain of unknown function (DUF1741)

    4. XM_017590385.3 → XP_017445874.1  armadillo-like helical domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I5YBM4, A0A8I6A824
      Related
      ENSRNOP00000100717.1, ENSRNOT00000122914.1
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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