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    dnai2b dynein, axonemal, intermediate chain 2b [ Danio rerio (zebrafish) ]

    Gene ID: 101884977, updated on 2-Nov-2024

    Summary

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    Official Symbol
    dnai2bprovided by ZNC
    Official Full Name
    dynein, axonemal, intermediate chain 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131016-1
    See related
    Ensembl:ENSDARG00000074081 AllianceGenome:ZFIN:ZDB-GENE-131016-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dnai2
    Summary
    Predicted to be located in cell projection; cytoplasm; and microtubule. Predicted to be part of dynein complex. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 9. Orthologous to human DNAI2 (dynein axonemal intermediate chain 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dnai2b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (38693895..38713750)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (38519342..38537652)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L38 Neighboring gene tweety family member 2 Neighboring gene kinesin family member 19 Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein axonemal intermediate chain 2
    Names
    dynein, axonemal, intermediate chain 2
    zmp:0000000739

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      38693895..38713750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005156402.5 → XP_005156459.1  dynein axonemal intermediate chain 2

      UniProtKB/TrEMBL
      A0A8M2B2H1
      Related
      ENSDARP00000152440.1, ENSDART00000188726.1
      Conserved Domains (5) summary
      COG2319
      Location:168 → 495
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:169 → 215
      7WD40; WD40 repeat [structural motif]
      cd16269
      Location:567 → 578
      GBP_C; coiled coil [structural motif]
      cl02567
      Location:223 → 477
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl20817
      Location:489 → 588
      GBP_C; Guanylate-binding protein, C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials