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    pigg phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) [ Danio rerio (zebrafish) ]

    Gene ID: 100538291, updated on 17-Aug-2024

    Summary

    Official Symbol
    piggprovided by ZNC
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-141215-6
    See related
    Ensembl:ENSDARG00000038270 AllianceGenome:ZFIN:ZDB-GENE-141215-6
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch73-49o8.1
    Summary
    Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (3717768..3944029, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (3610737..3837032, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase pi 1.2 Neighboring gene farnesyltransferase, CAAX box, subunit alpha Neighboring gene LRP2 binding protein Neighboring gene sorting nexin 25 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mannose-ethanolamine phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GPI ethanolamine phosphate transferase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      3717768..3944029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009307684.3XP_009305959.1  GPI ethanolamine phosphate transferase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B8D1
      Conserved Domains (2) summary
      COG1524
      Location:28286
      Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
      cd16024
      Location:66335
      GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
    2. XM_005173072.4XP_005173129.1  GPI ethanolamine phosphate transferase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BKB6, E7FE54
      Related
      ENSDARP00000055816.5, ENSDART00000055817.7
      Conserved Domains (2) summary
      COG1524
      Location:28286
      Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
      cd16024
      Location:66335
      GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G