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    baiap2b BAR/IMD domain containing adaptor protein 2b [ Danio rerio (zebrafish) ]

    Gene ID: 100537012, updated on 2-Nov-2024

    Summary

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    Official Symbol
    baiap2bprovided by ZNC
    Official Full Name
    BAR/IMD domain containing adaptor protein 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100812-7
    See related
    Ensembl:ENSDARG00000103333 AllianceGenome:ZFIN:ZDB-GENE-100812-7
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable cytoskeletal anchor activity. Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to act upstream of or within plasma membrane organization and regulation of actin cytoskeleton organization. Predicted to be located in several cellular components, including cytoskeleton; filopodium; and ruffle. Predicted to be active in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See baiap2b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (35606346..35692562)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (35911928..36004511)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene SEC24 homolog C, COPII coat complex component Neighboring gene charged multivesicular body protein 6b Neighboring gene microRNA 338-1 Neighboring gene apoptosis-associated tyrosine kinase b Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cytoskeletal anchor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin crosslink formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin filament bundle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within plasma membrane organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in filopodium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ruffle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BAR/IMD domain-containing adapter protein 2
    Names
    BAI1-associated protein 2b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      35606346..35692562
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224811.1 → XP_068080912.1  BAR/IMD domain-containing adapter protein 2 isoform X4

    2. XM_068224808.1 → XP_068080909.1  BAR/IMD domain-containing adapter protein 2 isoform X2

    3. XM_068224810.1 → XP_068080911.1  BAR/IMD domain-containing adapter protein 2 isoform X4

    4. XM_068224807.1 → XP_068080908.1  BAR/IMD domain-containing adapter protein 2 isoform X1

    5. XM_068224809.1 → XP_068080910.1  BAR/IMD domain-containing adapter protein 2 isoform X3

    6. XM_068224813.1 → XP_068080914.1  BAR/IMD domain-containing adapter protein 2 isoform X6

    7. XM_068224812.1 → XP_068080913.1  BAR/IMD domain-containing adapter protein 2 isoform X5

    8. XM_068224814.1 → XP_068080915.1  BAR/IMD domain-containing adapter protein 2 isoform X7

      Related
      ENSDARP00000138148.2, ENSDART00000169889.2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394858.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      10718..73875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218693.1 → XP_068074794.1  BAR/IMD domain-containing adapter protein 2 isoform X10

    2. XM_068218690.1 → XP_068074791.1  BAR/IMD domain-containing adapter protein 2 isoform X8

    3. XM_068218692.1 → XP_068074793.1  BAR/IMD domain-containing adapter protein 2 isoform X10

    4. XM_068218691.1 → XP_068074792.1  BAR/IMD domain-containing adapter protein 2 isoform X9

    5. XM_068218695.1 → XP_068074796.1  BAR/IMD domain-containing adapter protein 2 isoform X12

    6. XM_068218697.1 → XP_068074798.1  BAR/IMD domain-containing adapter protein 2 isoform X13

    7. XM_068218694.1 → XP_068074795.1  BAR/IMD domain-containing adapter protein 2 isoform X11

    8. XM_068218696.1 → XP_068074797.1  BAR/IMD domain-containing adapter protein 2 isoform X7

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395304.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      10718..74100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219314.1 → XP_068075415.1  BAR/IMD domain-containing adapter protein 2 isoform X20

    2. XM_068219311.1 → XP_068075412.1  BAR/IMD domain-containing adapter protein 2 isoform X18

    3. XM_068219313.1 → XP_068075414.1  BAR/IMD domain-containing adapter protein 2 isoform X19

    4. XM_068219309.1 → XP_068075410.1  BAR/IMD domain-containing adapter protein 2 isoform X15

    5. XM_068219312.1 → XP_068075413.1  BAR/IMD domain-containing adapter protein 2 isoform X19

    6. XM_068219308.1 → XP_068075409.1  BAR/IMD domain-containing adapter protein 2 isoform X14

    7. XM_068219310.1 → XP_068075411.1  BAR/IMD domain-containing adapter protein 2 isoform X17

    8. XM_068219316.1 → XP_068075417.1  BAR/IMD domain-containing adapter protein 2 isoform X22

    9. XM_021474262.2 → XP_021329937.1  BAR/IMD domain-containing adapter protein 2 isoform X16

      UniProtKB/TrEMBL
      A0A8M9PFG9
      Conserved Domains (2) summary
      cd11915
      Location:332 → 390
      SH3_Irsp53; Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53
      cl12013
      Location:1 → 187
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    10. XM_068219315.1 → XP_068075416.1  BAR/IMD domain-containing adapter protein 2 isoform X21

    Nucleotide Protein Strain
    Heading Accession and Version

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