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    znfx1 zinc finger, NFX1-type containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100536767, updated on 2-Nov-2024

    Summary

    Official Symbol
    znfx1provided by ZNC
    Official Full Name
    zinc finger, NFX1-type containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-110804-2
    See related
    AllianceGenome:ZFIN:ZDB-GENE-110804-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb60c02; wu:fb60c02; si:zfos-1537b9.1
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ZNFX1 (zinc finger NFX1-type containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See znfx1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (57398626..57431560, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (57403329..57434677, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496032 Neighboring gene cadherin-22 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 Neighboring gene small nuclear ribonucleoprotein polypeptides B and B1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear RNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NFX1-type zinc finger-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      57398626..57431560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477327.2XP_021333002.1  NFX1-type zinc finger-containing protein 1

      UniProtKB/TrEMBL
      A0A8M9PND3
      Conserved Domains (3) summary
      pfam13087
      Location:11431327
      AAA_12; AAA domain
      pfam15042
      Location:15111629
      LELP1; Late cornified envelope-like proline-rich protein 1
      cl26261
      Location:9851134
      AAA_11; AAA domain
    2. XM_021477326.2XP_021333001.1  NFX1-type zinc finger-containing protein 1

      UniProtKB/TrEMBL
      A0A8M9PND3
      Conserved Domains (3) summary
      pfam13087
      Location:11431327
      AAA_12; AAA domain
      pfam15042
      Location:15111629
      LELP1; Late cornified envelope-like proline-rich protein 1
      cl26261
      Location:9851134
      AAA_11; AAA domain