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    top1 DNA topoisomerase I gene 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100496521, updated on 17-Aug-2024

    Summary

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    Official Symbol
    top1provided by Xenbase
    Official Full Name
    DNA topoisomerase I gene 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-950002
    See related
    Ensembl:ENSXETG00000040254
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    topi; top1.1
    Orthologs
    human mouse all
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    Genomic context

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    See top1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (40917733..40939392, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (32490498..32511580, complement)

    Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene DEAH-box helicase 35 Neighboring gene v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B Neighboring gene phospholipase C gamma 1 Neighboring gene zinc fingers and homeoboxes 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA topoisomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA topological change IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within rhythmic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA topoisomerase 1
    Names
    topoisomerase (DNA) I, gene 1
    topoisomerase DNA 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      40917733..40939392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002932872.5 → XP_002932918.2  DNA topoisomerase 1

      UniProtKB/TrEMBL
      A0A6I8QED0, A0A6I8RDS1
      Related
      ENSXETP00000071121.2, ENSXETT00000070565.2
      Conserved Domains (3) summary
      smart00435
      Location:399 → 776
      TOPEUc; DNA Topoisomerase I (eukaryota)
      TIGR01622
      Location:76 → 195
      SF-CC1; splicing factor, CC1-like family
      pfam02919
      Location:254 → 468
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment
    Nucleotide Protein Strain
    Heading Accession and Version

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