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    runx1t1 RUNX1 translocation partner 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100491944, updated on 14-Nov-2024

    Summary

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    Official Symbol
    runx1t1provided by Xenbase
    Official Full Name
    RUNX1 translocation partner 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-481238
    See related
    Ensembl:ENSXETG00000014592 AllianceGenome:Xenbase:XB-GENE-481238
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    MTG8
    Summary
    Predicted to enable metal ion binding activity and transcription corepressor activity. Predicted to act upstream of or within DNA-templated transcription and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See runx1t1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (126989497..127089647, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (111977650..112077669, complement)

    Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene solute carrier family 26 (anion exchanger), member 7 Neighboring gene keratin-associated protein 4-3 Neighboring gene transfer RNA glutamine (anticodon CUG)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein CBFA2T1
    Names
    runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      126989497..127089647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002934415.5 → XP_002934461.1  protein CBFA2T1 isoform X2

      UniProtKB/TrEMBL
      A0A6I8SC42, F6TEY3
      Related
      ENSXETP00000094548.1, ENSXETT00000087819.2
      Conserved Domains (4) summary
      COG2811
      Location:423 → 489
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam01753
      Location:495 → 531
      zf-MYND; MYND finger
      pfam07531
      Location:102 → 191
      TAFH; NHR1 homology to TAF
      pfam08788
      Location:317 → 383
      NHR2; NHR2 domain like

    2. XM_004915148.3 → XP_004915205.1  protein CBFA2T1 isoform X1

      UniProtKB/TrEMBL
      A0A5S6MBM4, A0A6I8R2R1, A0A6I8RUK8
      Related
      ENSXETP00000074787.2, ENSXETT00000088172.2
      Conserved Domains (4) summary
      COG2811
      Location:424 → 490
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam01753
      Location:496 → 532
      zf-MYND; MYND finger
      pfam07531
      Location:103 → 192
      TAFH; NHR1 homology to TAF
      pfam08788
      Location:318 → 384
      NHR2; NHR2 domain like

    3. XM_004915150.4 → XP_004915207.1  protein CBFA2T1 isoform X4

      UniProtKB/TrEMBL
      A0A6I8RUK8, A0A8J0R4S3
      Related
      ENSXETP00000031916.5, ENSXETT00000031916.5
      Conserved Domains (4) summary
      COG2811
      Location:406 → 472
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam01753
      Location:478 → 514
      zf-MYND; MYND finger
      pfam07531
      Location:85 → 174
      TAFH; NHR1 homology to TAF
      pfam08788
      Location:300 → 366
      NHR2; NHR2 domain like

    4. XM_004915149.4 → XP_004915206.1  protein CBFA2T1 isoform X3

      UniProtKB/TrEMBL
      A0A6I8QIM7, F6TEY3
      Related
      ENSXETP00000072776.2, ENSXETT00000075761.2
      Conserved Domains (4) summary
      pfam01753
      Location:489 → 525
      zf-MYND; MYND finger
      pfam07531
      Location:96 → 185
      TAFH; NHR1 homology to TAF
      pfam08788
      Location:311 → 377
      NHR2; NHR2 domain like
      cl23750
      Location:415 → 471
      vATP-synt_E; ATP synthase (E/31 kDa) subunit
    Nucleotide Protein Strain
    Heading Accession and Version

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