rere arginine-glutamic acid dipeptide repeats [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: rereprovided by Xenbase
Official Full Name: arginine-glutamic acid dipeptide repeatsprovided by Xenbase
Primary source: Xenbase:XB-GENE-919902
See related: Ensembl:ENSXETG00000011890 AllianceGenome:Xenbase:XB-GENE-919902
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: dnb1; atn1l
Summary: Predicted to enable transcription corepressor activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 31

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	7	NC_030683.2 (89377272..89587372, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	7	NC_030683.1 (80326278..80535374, complement)

Chromosome 7 - NC_030683.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables chromatin binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: arginine-glutamic acid dipeptide repeats protein

Names: arginine-glutamic acid dipeptide (RE) repeats

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

89377272..89587372 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_031905585.1 → XP_031761445.1 arginine-glutamic acid dipeptide repeats protein isoform X2

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JWP3
XM_002936381.5 → XP_002936427.2 arginine-glutamic acid dipeptide repeats protein isoform X1

See identical proteins and their annotated locations for XP_002936427.2

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_004916132.4 → XP_004916189.1 arginine-glutamic acid dipeptide repeats protein isoform X1

See identical proteins and their annotated locations for XP_004916189.1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Related

ENSXETP00000087040.2, ENSXETT00000081197.2

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905578.1 → XP_031761438.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_018096039.2 → XP_017951528.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905579.1 → XP_031761439.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905580.1 → XP_031761440.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905581.1 → XP_031761441.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905586.1 → XP_031761446.1 arginine-glutamic acid dipeptide repeats protein isoform X3

UniProtKB/TrEMBL

A0A6I8QDU1, A0A6I8RWF4

Related

ENSXETP00000070920.2, ENSXETT00000077474.2

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1515

Atrophin-1; Atrophin-1 family
XM_031905584.1 → XP_031761444.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905582.1 → XP_031761442.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_031905583.1 → XP_031761443.1 arginine-glutamic acid dipeptide repeats protein isoform X1

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J1JU86

Conserved Domains (5) summary

cd11661
Location:349 → 394

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

cd00202
Location:460 → 514

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

cd04709
Location:98 → 260

BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...

pfam01448
Location:240 → 290

ELM2; ELM2 domain

pfam03154
Location:522 → 1539

Atrophin-1; Atrophin-1 family
XM_004916140.1 → XP_004916197.1 arginine-glutamic acid dipeptide repeats protein isoform X4

UniProtKB/TrEMBL

A0A6I8RWF4, A0A8J0R174

Conserved Domains (7) summary

smart00717
Location:128 → 173

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

cd11661
Location:127 → 172

SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins

smart00401
Location:235 → 284

ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]

cd00202
Location:238 → 292

ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

pfam01448
Location:18 → 68

ELM2; ELM2 domain

pfam03154
Location:300 → 1317

Atrophin-1; Atrophin-1 family

pfam14650
Location:534 → 624

FAM75; FAM75 family