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    dock5 dedicator of cytokinesis 5 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100488768, updated on 4-Nov-2024

    Summary

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    Official Symbol
    dock5provided by Xenbase
    Official Full Name
    dedicator of cytokinesis 5provided by Xenbase
    Primary source
    Xenbase:XB-GENE-490920
    See related
    Ensembl:ENSXETG00000031383 AllianceGenome:Xenbase:XB-GENE-490920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within cell migration and small GTPase-mediated signal transduction. Predicted to be located in cytoplasm. Orthologous to human DOCK5 (dedicator of cytokinesis 5). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dock5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (127686797..127732685)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (106535087..106572959, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene neurofilament medium chain Neighboring gene neurofilament light chain Neighboring gene gonadotropin releasing hormone 1 Neighboring gene potassium channel tetramerization domain containing 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dedicator of cytokinesis protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      127686797..127732685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004912550.4 → XP_004912607.1  dedicator of cytokinesis protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A6I8QES5
      Related
      ENSXETP00000067042.2, ENSXETT00000102339.2
      Conserved Domains (4) summary
      cd11708
      Location:1232 → 1631
      DHR2_DOCK5; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 5
      pfam16172
      Location:71 → 433
      DOCK_N; DOCK N-terminus
      cl14603
      Location:441 → 632
      C2; C2 domain
      cl17036
      Location:12 → 67
      SH3; Src Homology 3 domain superfamily

    2. XM_002932583.5 → XP_002932629.2  dedicator of cytokinesis protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A8J0QJ89
      Conserved Domains (4) summary
      cd11708
      Location:1232 → 1631
      DHR2_DOCK5; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 5
      pfam16172
      Location:71 → 433
      DOCK_N; DOCK N-terminus
      cl14603
      Location:441 → 632
      C2; C2 domain
      cl17036
      Location:12 → 67
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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