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    si:ch1073-429i10.1 si:ch1073-429i10.1 [ Danio rerio (zebrafish) ]

    Gene ID: 100332057, updated on 2-Nov-2024

    Summary

    Official Symbol
    si:ch1073-429i10.1provided by ZNC
    Official Full Name
    si:ch1073-429i10.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120215-259
    See related
    Ensembl:ENSDARG00000075664 AllianceGenome:ZFIN:ZDB-GENE-120215-259
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable delta14-sterol reductase activity. Predicted to be involved in cholesterol biosynthetic process. Predicted to act upstream of or within cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane and nuclear inner membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See si:ch1073-429i10.1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (47867133..47874822, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (47279510..47288909, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:ch1073-429i10.3 Neighboring gene H3 histone, family 3B.1 Neighboring gene zmp:0000000529 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables delta14-sterol reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-CH group of donors IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    delta(14)-sterol reductase TM7SF2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      47867133..47874822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002664757.7XP_002664803.1  delta(14)-sterol reductase TM7SF2

      See identical proteins and their annotated locations for XP_002664803.1

      UniProtKB/TrEMBL
      A0A8M1RHQ1, I3IRZ4
      Related
      ENSDARP00000125656.1, ENSDART00000151606.2
      Conserved Domains (1) summary
      cl21511
      Location:84438
      PEMT; Phospholipid methyltransferase