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    dnah2 dynein, axonemal, heavy chain 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100170584, updated on 17-Aug-2024

    Summary

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    Official Symbol
    dnah2provided by Xenbase
    Official Full Name
    dynein, axonemal, heavy chain 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5967455
    See related
    Ensembl:ENSXETG00000008299
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    See dnah2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    89
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (147082578..147201168, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683579.1 (14140..152803, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100489710 Neighboring gene lysine (K)-specific demethylase 6B Neighboring gene ephrin-B3 Neighboring gene uncharacterized LOC101730300 Neighboring gene estradiol 17-beta-dehydrogenase 12-B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dynein intermediate chain binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dynein light intermediate chain binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables minus-end-directed microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in axoneme IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dynein heavy chain 2, axonemal

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      147082578..147201168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031899560.1 → XP_031755420.1  dynein heavy chain 2, axonemal isoform X2

      UniProtKB/TrEMBL
      A0A8J1JEG2
      Conserved Domains (4) summary
      COG5245
      Location:1188 → 4127
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08385
      Location:222 → 783
      DHC_N1; Dynein heavy chain, N-terminal region 1
      pfam12774
      Location:1826 → 2152
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:4183 → 4484
      Dynein_C; Dynein heavy chain C-terminal domain

    2. XM_031899559.1 → XP_031755419.1  dynein heavy chain 2, axonemal isoform X1

      UniProtKB/TrEMBL
      F7DZ81
      Related
      ENSXETP00000018198.5, ENSXETT00000018198.5
      Conserved Domains (4) summary
      COG5245
      Location:1193 → 4132
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08385
      Location:227 → 788
      DHC_N1; Dynein heavy chain, N-terminal region 1
      pfam12774
      Location:1831 → 2157
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:4188 → 4489
      Dynein_C; Dynein heavy chain C-terminal domain

    3. XM_031899561.1 → XP_031755421.1  dynein heavy chain 2, axonemal isoform X3

      UniProtKB/TrEMBL
      A0A8J1JFI7
      Conserved Domains (3) summary
      COG5245
      Location:305 → 3244
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam12774
      Location:943 → 1269
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:3300 → 3601
      Dynein_C; Dynein heavy chain C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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