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    dna2 DNA replication helicase/nuclease 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100170166, updated on 17-Aug-2024

    Summary

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    Official Symbol
    dna2provided by Xenbase
    Official Full Name
    DNA replication helicase/nuclease 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5828964
    See related
    Ensembl:ENSXETG00000007483
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    dna2l; xdna2
    Orthologs
    human mouse all
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    Genomic context

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    See dna2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (40314298..40345706)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (32128022..32158396)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene zinc finger, AN1-type domain 4 Neighboring gene WASH complex subunit 2A Neighboring gene beta-microseminoprotein Neighboring gene microseminoprotein, beta-, gene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 5'-flap endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA replication, Okazaki fragment processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA replication ATP-dependent helicase/nuclease DNA2
    Names
    DNA replication helicase 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      40314298..40345706
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002935970.4 → XP_002936016.2  DNA replication ATP-dependent helicase/nuclease DNA2

      UniProtKB/TrEMBL
      A0A5S6L447, A0A8J0QRW9
      Related
      ENSXETP00000068845.2, ENSXETT00000084854.2
      Conserved Domains (4) summary
      TIGR00376
      Location:469 → 1037
      TIGR00376; DNA helicase, putative
      cd18041
      Location:626 → 829
      DEXXQc_DNA2; DEXXQ-box helicase domain of DNA2
      pfam08696
      Location:76 → 283
      Dna2; DNA replication factor Dna2
      cl00641
      Location:262 → 358
      Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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