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    nalf1a NALCN channel auxiliary factor 1a [ Danio rerio (zebrafish) ]

    Gene ID: 100149983, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nalf1aprovided by ZNC
    Official Full Name
    NALCN channel auxiliary factor 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-34
    See related
    Ensembl:ENSDARG00000075858 AllianceGenome:ZFIN:ZDB-GENE-090313-34
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nalf1; fam155a; si:ch211-144m15.1
    Summary
    Predicted to contribute to stretch-activated, monoatomic cation-selective, calcium channel activity. Predicted to be involved in calcium ion import across plasma membrane. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human NALF1 (NALCN channel auxiliary factor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nalf1a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (29281807..29394041)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (28476210..28586469)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene insulin receptor substrate 2a Neighboring gene ligase IV, DNA, ATP-dependent Neighboring gene uncharacterized LOC137495312 Neighboring gene cholecystokinin B receptor a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Biswas G, et al. Mar Genomics, 2015 Aug. PMID 25792259
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to stretch-activated, monoatomic cation-selective, calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NALCN channel auxiliary factor 1
    Names
    family with sequence similarity 155 member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      29281807..29394041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001921192.6 → XP_001921227.1  NALCN channel auxiliary factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QKK1, E7FA63
      Related
      ENSDARP00000098845.3, ENSDART00000112106.4

    2. XM_009291932.4 → XP_009290207.1  NALCN channel auxiliary factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B1B8
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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