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    dennd2d DENN/MADD domain containing 2D [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100145288, updated on 4-Nov-2024

    Summary

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    Official Symbol
    dennd2dprovided by Xenbase
    Official Full Name
    DENN/MADD domain containing 2Dprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-5816391
    See related
    Ensembl:ENSXETG00000004388 AllianceGenome:Xenbase:XB-GENE-5816391
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity. Orthologous to human DENND2D (DENN domain containing 2D). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dennd2d in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (64403215..64494690, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (77721082..77812666, complement)

    Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1A Neighboring gene uncharacterized LOC116408826 Neighboring gene choline/ethanolamine phosphotransferase 1 Neighboring gene neurofascin Neighboring gene contactin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DENN domain-containing protein 2D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126766.1 → NP_001120238.1  DENN domain-containing protein 2D

      See identical proteins and their annotated locations for NP_001120238.1

      Status: PROVISIONAL

      Source sequence(s)
      BC160418
      UniProtKB/TrEMBL
      A0A6I8SY78, B1H103
      Related
      ENSXETP00000009561.3, ENSXETT00000009561.5
      Conserved Domains (3) summary
      smart00801
      Location:366 → 430
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:45 → 136
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:143 → 327
      DENN; DENN (AEX-3) domain

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      64403215..64494690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012955901.3 → XP_012811355.1  DENN domain-containing protein 2D isoform X1

      UniProtKB/TrEMBL
      A0A6I8SY78, F7CWX4
      Conserved Domains (3) summary
      smart00801
      Location:366 → 430
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:45 → 136
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:143 → 327
      DENN; DENN (AEX-3) domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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