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    ids iduronate 2-sulfatase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100135738, updated on 4-Nov-2024

    Summary

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    Official Symbol
    idsprovided by Xenbase
    Official Full Name
    iduronate 2-sulfataseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-972154
    See related
    Ensembl:ENSXETG00000007745 AllianceGenome:Xenbase:XB-GENE-972154
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    mps2; sids
    Summary
    Predicted to enable iduronate-2-sulfatase activity. Human ortholog(s) of this gene implicated in mucopolysaccharidosis II. Orthologous to human IDS (iduronate 2-sulfatase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ids in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (57525979..57535155, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (36350730..36359963, complement)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene fragile X messenger ribonucleoprotein 1 Neighboring gene AF4/FMR2 family member 2 Neighboring gene transmembrane protein 185A Neighboring gene uncharacterized LOC116406926 Neighboring gene mastermind like domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iduronate-2-sulfatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    iduronate 2-sulfatase
    NP_001184061.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001197132.1 → NP_001184061.1  iduronate 2-sulfatase precursor

      Status: VALIDATED

      Source sequence(s)
      AAMC04000008, CU025186
      UniProtKB/TrEMBL
      A8WGX6, F7CIX8
      Related
      ENSXETP00000016900.4, ENSXETT00000016900.5
      Conserved Domains (1) summary
      cd16030
      Location:34 → 526
      iduronate-2-sulfatase

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      57525979..57535155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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