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    h6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100127695, updated on 17-Aug-2024

    Summary

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    Official Symbol
    h6pdprovided by Xenbase
    Official Full Name
    hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)provided by Xenbase
    Primary source
    Xenbase:XB-GENE-988586
    See related
    Ensembl:ENSXETG00000012078
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    See h6pd in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (89805026..89837061)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (80749337..80804213)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 157 Neighboring gene uncharacterized LOC116412312 Neighboring gene microRNA mir-34a Neighboring gene splA/ryanodine receptor domain and SOCS box containing 1 Neighboring gene TNF receptor superfamily member 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables 6-phosphogluconolactonase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucose-6-phosphate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GDH/6PGL endoplasmic bifunctional protein
    NP_001106505.1
    XP_031760646.1
    XP_031760647.1
    XP_031760648.1
    XP_031760649.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113034.1 → NP_001106505.1  GDH/6PGL endoplasmic bifunctional protein precursor

      See identical proteins and their annotated locations for NP_001106505.1

      Status: PROVISIONAL

      Source sequence(s)
      BC154708
      UniProtKB/TrEMBL
      A8WGH0
      Conserved Domains (4) summary
      TIGR00871
      Location:25 → 523
      zwf; glucose-6-phosphate 1-dehydrogenase
      pfam00479
      Location:29 → 211
      G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
      pfam01182
      Location:558 → 780
      Glucosamine_iso; Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
      pfam02781
      Location:225 → 523
      G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      89805026..89837061
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031904787.1 → XP_031760647.1  GDH/6PGL endoplasmic bifunctional protein isoform X1

      UniProtKB/TrEMBL
      F7BV51
      Conserved Domains (2) summary
      PTZ00309
      Location:38 → 518
      PTZ00309; glucose-6-phosphate 1-dehydrogenase; Provisional
      pfam01182
      Location:570 → 792
      Glucosamine_iso; Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase

    2. XM_031904786.1 → XP_031760646.1  GDH/6PGL endoplasmic bifunctional protein isoform X1

      UniProtKB/TrEMBL
      F7BV51
      Related
      ENSXETP00000026356.4, ENSXETT00000026356.4
      Conserved Domains (2) summary
      PTZ00309
      Location:38 → 518
      PTZ00309; glucose-6-phosphate 1-dehydrogenase; Provisional
      pfam01182
      Location:570 → 792
      Glucosamine_iso; Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase

    3. XM_031904788.1 → XP_031760648.1  GDH/6PGL endoplasmic bifunctional protein isoform X1

      UniProtKB/TrEMBL
      F7BV51
      Conserved Domains (2) summary
      PTZ00309
      Location:38 → 518
      PTZ00309; glucose-6-phosphate 1-dehydrogenase; Provisional
      pfam01182
      Location:570 → 792
      Glucosamine_iso; Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase

    4. XM_031904789.1 → XP_031760649.1  GDH/6PGL endoplasmic bifunctional protein isoform X2

      UniProtKB/TrEMBL
      A0A8J1JRY2
      Conserved Domains (2) summary
      PTZ00309
      Location:26 → 506
      PTZ00309; glucose-6-phosphate 1-dehydrogenase; Provisional
      pfam01182
      Location:558 → 780
      Glucosamine_iso; Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
    Nucleotide Protein Strain
    Heading Accession and Version

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