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    slain1 SLAIN motif family member 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100127571, updated on 4-Nov-2024

    Summary

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    Official Symbol
    slain1provided by Xenbase
    Official Full Name
    SLAIN motif family member 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5793178
    See related
    Ensembl:ENSXETG00000015457 AllianceGenome:Xenbase:XB-GENE-5793178
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to be involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to colocalize with microtubule plus-end. Orthologous to human SLAIN1 (SLAIN motif family member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slain1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (125955486..125994047, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (122614701..122652962, complement)

    Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene endothelin receptor type B Neighboring gene uncharacterized protein K02A2.6-like Neighboring gene sciellin Neighboring gene MYC binding protein 2, E3 ubiquitin protein ligase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of microtubule polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    colocalizes_with microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SLAIN motif-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001112938.1 → NP_001106409.2  SLAIN motif-containing protein 1

      See identical proteins and their annotated locations for NP_001106409.2

      Status: VALIDATED

      Source sequence(s)
      BC153339
      UniProtKB/Swiss-Prot
      A8E4V2
      UniProtKB/TrEMBL
      A0A803K6A1
      Related
      ENSXETP00000033732.4, ENSXETT00000033732.4
      Conserved Domains (1) summary
      pfam15301
      Location:164 → 545
      SLAIN; SLAIN motif-containing family

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      125955486..125994047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012956338.2 → XP_012811792.1  SLAIN motif-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A803K6A1, A0A8J0SEI7
      Related
      ENSXETP00000115785.1, ENSXETT00000122907.1
      Conserved Domains (1) summary
      pfam15301
      Location:164 → 592
      SLAIN; SLAIN motif-containing family

    2. XM_012956340.3 → XP_012811794.1  SLAIN motif-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8J0S703
      Conserved Domains (1) summary
      pfam15301
      Location:11 → 438
      SLAIN; SLAIN motif-containing family

    3. XM_012956339.3 → XP_012811793.1  SLAIN motif-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A803J940, F6RQ94
      Related
      ENSXETP00000033730.4, ENSXETT00000033730.5
      Conserved Domains (1) summary
      pfam15301
      Location:166 → 547
      SLAIN; SLAIN motif-containing family

    4. XM_012956337.3 → XP_012811791.1  SLAIN motif-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A803J940, A0A803JJF4
      Related
      ENSXETP00000108069.1, ENSXETT00000124469.1
      Conserved Domains (1) summary
      pfam15301
      Location:166 → 594
      SLAIN; SLAIN motif-containing family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8E4V2.2 GenPept UniProtKB/Swiss-Prot:A8E4V2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.