U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    tctn1 tectonic family member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100007222, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    tctn1provided by ZNC
    Official Full Name
    tectonic family member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-157
    See related
    Ensembl:ENSDARG00000078447 AllianceGenome:ZFIN:ZDB-GENE-081104-157
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-193e13.1
    Summary
    Predicted to be involved in cilium assembly and protein localization to ciliary transition zone. Predicted to act upstream of or within cell projection organization. Predicted to be part of MKS complex. Human ortholog(s) of this gene implicated in Joubert syndrome 13. Orthologous to human TCTN1 (tectonic family member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See tctn1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (8416073..8434805, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (8457373..8476110, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 1a Neighboring gene hydrogen voltage-gated channel 1 Neighboring gene protein phosphatase targeting COQ7 b Neighboring gene C-type lectin domain family 12 member B-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants. Wang J, et al. Dis Model Mech, 2022 Dec 1. PMID 36533556, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to ciliary transition zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of MKS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    tectonic family member 1; tectonic-1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      8416073..8434805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009305137.3 → XP_009303412.1  tectonic-1

      UniProtKB/TrEMBL
      A0A8M3B620, F1R392
      Related
      ENSDARP00000104299.3, ENSDART00000108643.4
      Conserved Domains (1) summary
      pfam07773
      Location:110 → 336
      DUF1619; Protein of unknown function (DUF1619)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials