etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: etfbkmtprovided by ZNC
Official Full Name: electron transfer flavoprotein subunit beta lysine methyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-111107-1
See related: Ensembl:ENSDARG00000079080 AllianceGenome:ZFIN:ZDB-GENE-111107-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mettl20; ETFB-KMT
Summary: Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to act upstream of or within methylation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (28907798..28926618, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (28464596..28483416, complement)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-lysine N-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-lysine N-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: electron transfer flavoprotein beta subunit lysine methyltransferase

Names: ETFB lysine methyltransferase; UPF0516 protein; methyltransferase like 20; methyltransferase-like protein 20; protein N-lysine methyltransferase METTL20

NP_001154967.1

EC 2.1.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001161495.1 → NP_001154967.1 electron transfer flavoprotein beta subunit lysine methyltransferase

See identical proteins and their annotated locations for NP_001154967.1

Status: PROVISIONAL

Source sequence(s)

BC134209

UniProtKB/Swiss-Prot

A3KP85

Related

ENSDARP00000103806.1, ENSDART00000112850.4

Conserved Domains (1) summary

COG3897
Location:38 → 252

Nnt1; Predicted nicotinamide N-methyase [General function prediction only]