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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_034110.1 RefSeqGene
- Range
-
5075..9204
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001042529.3 → NP_001035994.1 bifunctional coenzyme A synthase isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a, also known as CoASy alpha).
- Source sequence(s)
-
AK225485, AY094602, DA786254
- Consensus CDS
-
CCDS11429.1
- UniProtKB/Swiss-Prot
- B2RA78, B4DLU0, Q13057, Q6GS23, Q8NBM7, Q8NEW1, Q8WXD4, Q9NRM3
- Related
- ENSP00000393564.2, ENST00000421097.6
- Conserved Domains (2) summary
-
- cd02164
Location:193 → 339
- PPAT_CoAS; phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes
- cd02022
Location:360 → 536
- DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
-
NM_001042532.4 → NP_001035997.2 bifunctional coenzyme A synthase isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and contains an additional segment in the 5' coding region, compared to variant 1. The resulting isoform (c, also known as CoASy beta) is longer at the N-terminus, compared to isoform a.
- Source sequence(s)
-
AK297153, AK314076, BC020985, DA786254
- Consensus CDS
-
CCDS45685.1
- UniProtKB/Swiss-Prot
-
Q13057
- Related
- ENSP00000464814.1, ENST00000590958.5
- Conserved Domains (3) summary
-
- cd02164
Location:222 → 368
- PPAT_CoAS; phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes
- COG0237
Location:388 → 588
- CoaE; Dephospho-CoA kinase [Coenzyme transport and metabolism]
- cd02022
Location:389 → 565
- DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
-
NM_025233.7 → NP_079509.5 bifunctional coenzyme A synthase isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes isoform a (also known as CoASy alpha). Both variants 1 and 2 encode the same isoform.
- Source sequence(s)
-
AK075415, BC020985, BM781531, DA786254
- Consensus CDS
-
CCDS11429.1
- UniProtKB/Swiss-Prot
- B2RA78, B4DLU0, Q13057, Q6GS23, Q8NBM7, Q8NEW1, Q8WXD4, Q9NRM3
- Related
- ENSP00000377406.1, ENST00000393818.3
- Conserved Domains (2) summary
-
- cd02164
Location:193 → 339
- PPAT_CoAS; phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes
- cd02022
Location:360 → 536
- DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
42562148..42566277
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011525300.2 → XP_011523602.1 bifunctional coenzyme A synthase isoform X1
- UniProtKB/Swiss-Prot
- B2RA78, B4DLU0, Q13057, Q6GS23, Q8NBM7, Q8NEW1, Q8WXD4, Q9NRM3
- Conserved Domains (2) summary
-
- cd02164
Location:193 → 339
- PPAT_CoAS; phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes
- cd02022
Location:360 → 536
- DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
-
XM_047436849.1 → XP_047292805.1 bifunctional coenzyme A synthase isoform X2
-
XM_047436850.1 → XP_047292806.1 bifunctional coenzyme A synthase isoform X3
-
XM_006722116.5 → XP_006722179.1 bifunctional coenzyme A synthase isoform X4
- UniProtKB/Swiss-Prot
-
Q13057
- Conserved Domains (3) summary
-
- cd02164
Location:222 → 368
- PPAT_CoAS; phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes
- COG0237
Location:388 → 588
- CoaE; Dephospho-CoA kinase [Coenzyme transport and metabolism]
- cd02022
Location:389 → 565
- DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
43419336..43423465
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054317411.1 → XP_054173386.1 bifunctional coenzyme A synthase isoform X1
- UniProtKB/Swiss-Prot
- B2RA78, B4DLU0, Q13057, Q6GS23, Q8NBM7, Q8NEW1, Q8WXD4, Q9NRM3
-
XM_054317412.1 → XP_054173387.1 bifunctional coenzyme A synthase isoform X2
-
XM_054317413.1 → XP_054173388.1 bifunctional coenzyme A synthase isoform X3
-
XM_054317414.1 → XP_054173389.1 bifunctional coenzyme A synthase isoform X4
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001042530.1: Suppressed sequence
- Description
- NM_001042530.1: This RefSeq was permanently suppressed because currently there is insufficient support for the full-length nature of the transcript.
-
NM_001042531.1: Suppressed sequence
- Description
- NM_001042531.1: This RefSeq was permanently suppressed because currently there is insufficient support for the protein, and the full-length nature of this transcript variant is unknown.