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    CAPN10 calpain 10 [ Bos taurus (domestic cattle) ]

    Gene ID: 789674, updated on 10-Oct-2024

    Summary

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    Official Symbol
    CAPN10provided by VGNC
    Official Full Name
    calpain 10provided by VGNC
    Primary source
    VGNC:VGNC:26741
    See related
    BGD:BT18499; Ensembl:ENSBTAG00000002809
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CAPN10 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (119973240..119983822)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene arginyl aminopeptidase like 1 Neighboring gene uncharacterized LOC132344960 Neighboring gene G protein-coupled receptor 35 Neighboring gene aquaporin 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-10
    Names
    calpain-10-like
    XP_024846093.1
    XP_024846095.1
    XP_024846100.1
    XP_059741275.1
    XP_059741276.1
    XP_059741278.1
    XP_059741279.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      119973240..119983822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059885292.1 → XP_059741275.1  calpain-10 isoform X3

    2. XM_059885293.1 → XP_059741276.1  calpain-10 isoform X4

    3. XM_024990325.2 → XP_024846093.1  calpain-10 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SXM9
      Conserved Domains (2) summary
      cd00044
      Location:5 → 314
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cd00214
      Location:332 → 471
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    4. XM_024990332.2 → XP_024846100.1  calpain-10 isoform X5

      UniProtKB/TrEMBL
      A0AAA9SXM9
      Related
      ENSBTAP00000088061.1, ENSBTAT00000108901.1
      Conserved Domains (2) summary
      cd00044
      Location:5 → 314
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cd00214
      Location:332 → 471
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    5. XM_024990327.2 → XP_024846095.1  calpain-10 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SSZ8, A0AAA9SXM9
      Related
      ENSBTAP00000086158.1, ENSBTAT00000094314.1
      Conserved Domains (2) summary
      cd00044
      Location:5 → 314
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cd00214
      Location:332 → 471
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    6. XM_059885295.1 → XP_059741278.1  calpain-10 isoform X6

      UniProtKB/TrEMBL
      F1MBN8
      Related
      ENSBTAP00000003637.7, ENSBTAT00000003637.7

    7. XM_059885296.1 → XP_059741279.1  calpain-10 isoform X7

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001191254.1: Suppressed sequence

      Description
      NM_001191254.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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