U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    agl amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 780065, updated on 4-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    aglprovided by Xenbase
    Official Full Name
    amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-1001429
    See related
    Ensembl:ENSXETG00000013185 AllianceGenome:Xenbase:XB-GENE-1001429
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    gde; xagl
    Summary
    Predicted to enable 4-alpha-glucanotransferase activity and amylo-alpha-1,6-glucosidase activity. Predicted to act upstream of or within glycogen biosynthetic process and glycogen catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease III. Orthologous to human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See agl in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (108486093..108539477)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (98403989..98469544)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene pre-B-cell leukemia homeobox 1 Neighboring gene LIM homeobox transcription factor 1 alpha Neighboring gene putative ferric-chelate reductase 1 Neighboring gene putative ferric-chelate reductase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC146500

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables 4-alpha-glucanotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables amylo-alpha-1,6-glucosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within glycogen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase; glycogen debranching enzyme
    Names
    6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III)
    amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III)
    amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      108486093..108539477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031901015.1 → XP_031756875.1  glycogen debranching enzyme isoform X1

      UniProtKB/TrEMBL
      A0A6I8PYN9, F7D922
      Related
      ENSXETP00000097426.2, ENSXETT00000076880.2
      Conserved Domains (1) summary
      TIGR01531
      Location:22 → 1532
      glyc_debranch; glycogen debranching enzymye

    2. XM_031901016.1 → XP_031756876.1  glycogen debranching enzyme isoform X1

      UniProtKB/TrEMBL
      A0A6I8PYN9, F7D922
      Related
      ENSXETP00000028868.5, ENSXETT00000028868.5
      Conserved Domains (1) summary
      TIGR01531
      Location:22 → 1532
      glyc_debranch; glycogen debranching enzymye

    3. XM_031901017.1 → XP_031756877.1  glycogen debranching enzyme isoform X2

      UniProtKB/TrEMBL
      A0A6I8PYN9, A0A6I8SDS9
      Related
      ENSXETP00000092922.2, ENSXETT00000067573.2
      Conserved Domains (1) summary
      TIGR01531
      Location:22 → 1532
      glyc_debranch; glycogen debranching enzymye

    4. XM_031901012.1 → XP_031756872.1  glycogen debranching enzyme isoform X1

      UniProtKB/TrEMBL
      A0A6I8PYN9, F7D922
      Conserved Domains (1) summary
      TIGR01531
      Location:22 → 1532
      glyc_debranch; glycogen debranching enzymye

    5. XM_031901014.1 → XP_031756874.1  glycogen debranching enzyme isoform X1

      UniProtKB/TrEMBL
      A0A6I8PYN9, F7D922
      Conserved Domains (1) summary
      TIGR01531
      Location:22 → 1532
      glyc_debranch; glycogen debranching enzymye

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001079141.1: Suppressed sequence

      Description
      NM_001079141.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from cow: AGL (GeneID:517397).
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.