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    CD80 CD80 molecule [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 732518, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CD80provided by VGNC
    Official Full Name
    CD80 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:84205
    Locus tag
    EGK_11324
    See related
    Ensembl:ENSMMUG00000016367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    B7.1
    Orthologs
    human mouse all
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    Genomic context

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    See CD80 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (156709250..156741505)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (40694582..40727246, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene phospholipase A1 member A Neighboring gene ADP-ribosylarginine hydrolase Neighboring gene cysteine and glycine-rich protein 2 pseudogene Neighboring gene translocase of inner mitochondrial membrane domain containing 1 Neighboring gene protein O-glucosyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and comparative analysis of the rhesus macaque costimulatory molecules CD80 (B7-1) and CD86 (B7-2). Zhang D, et al. Cell Immunol, 1997 Apr 10. PMID 9140091
    2. Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules. Villinger F, et al. Immunogenetics, 2001 May-Jun. PMID 11491535
    3. Comparative sequence analysis of cytokine genes from human and nonhuman primates. Villinger F, et al. J Immunol, 1995 Oct 15. PMID 7561102
    4. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables coreceptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell costimulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-lymphocyte activation antigen CD80

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042642.2 → NP_001036107.2  T-lymphocyte activation antigen CD80 precursor

      See identical proteins and their annotated locations for NP_001036107.2

      Status: VALIDATED

      Source sequence(s)
      JU477896
      UniProtKB/TrEMBL
      A0A8J8YFK0, F7HRG1, G7MKE2, H9ZFI4
      Related
      ENSMMUP00000039953.2, ENSMMUT00000046921.3
      Conserved Domains (3) summary
      smart00410
      Location:37 → 138
      IG_like; Immunoglobulin like
      pfam08205
      Location:142 → 227
      C2-set_2; CD80-like C2-set immunoglobulin domain
      cl11960
      Location:37 → 134
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      156709250..156741505
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials