PRDX2 peroxiredoxin 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: PRDX2
Gene description: peroxiredoxin 2
Locus tag: EGK_10176
See related: Ensembl:ENSMMUG00000005689
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19	NC_041772.1 (12374890..12380145, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (12743242..12748507, complement)

Chromosome 19 - NC_041772.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

A005B41 (e-PCR)
- UniSTS:10307

PMC186344P1 (e-PCR)
- UniSTS:271701

G32220 (e-PCR)
- UniSTS:116826

PRDX2_3483 (e-PCR)
- UniSTS:462458

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables thioredoxin peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell redox homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to stress	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hydrogen peroxide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in leukocyte activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in removal of superoxide radicals	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: peroxiredoxin-2

NP_001248186.1

EC 1.11.1.24

EC 1.11.1.25

EC 1.11.1.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261257.1 → NP_001248186.1 peroxiredoxin-2

See identical proteins and their annotated locations for NP_001248186.1

Status: PROVISIONAL

Source sequence(s)

JV045655

UniProtKB/TrEMBL

A0A5F8AKU6, A0A663D6C7, A0A8J8XBE4, F6U5B4, G7NLB5

Related

ENSMMUP00000007512.4, ENSMMUT00000007992.4

Conserved Domains (1) summary

cd03015
Location:8 → 179

PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...