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    BCAR1 BCAR1 scaffold protein, Cas family member [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713965, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BCAR1provided by VGNC
    Official Full Name
    BCAR1 scaffold protein, Cas family memberprovided by VGNC
    Primary source
    VGNC:VGNC:70234
    See related
    Ensembl:ENSMMUG00000002630
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See BCAR1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (62206402..62251543, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (59517532..59556703, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B2 Neighboring gene chymotrypsinogen B Neighboring gene U6 spliceosomal RNA Neighboring gene craniofacial development protein 1 Neighboring gene uncharacterized LOC114674408

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    breast cancer anti-estrogen resistance protein 1
    Names
    BCAR1, Cas family scaffold protein
    BCAR1, Cas family scaffolding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      62206402..62251543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126628.2 → XP_014982114.1  breast cancer anti-estrogen resistance protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R6V3, F7H778, I0FWM3
      Related
      ENSMMUP00000056041.2, ENSMMUT00000075826.2
      Conserved Domains (3) summary
      cd12001
      Location:23 → 89
      SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
      pfam12026
      Location:673 → 882
      DUF3513; Domain of unknown function (DUF3513)
      cl07433
      Location:472 → 628
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

    2. XM_015126630.2 → XP_014982116.1  breast cancer anti-estrogen resistance protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A5F8AK84, H9G269
      Related
      ENSMMUP00000077426.1, ENSMMUT00000081547.1
      Conserved Domains (3) summary
      cd12001
      Location:5 → 71
      SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
      pfam12026
      Location:655 → 864
      DUF3513; Domain of unknown function (DUF3513)
      cl07433
      Location:454 → 610
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

    3. XM_028841205.1 → XP_028697038.1  breast cancer anti-estrogen resistance protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QBS0, F7H778
      Conserved Domains (4) summary
      cd12001
      Location:15 → 81
      SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
      PHA03247
      Location:93 → 407
      PHA03247; large tegument protein UL36; Provisional
      cl07433
      Location:464 → 620
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
      pfam12026
      Location:665 → 874
      DUF3513; Domain of unknown function (DUF3513)

    4. XM_028841207.1 → XP_028697040.1  breast cancer anti-estrogen resistance protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5QBS0, A0A1D5QE98, F7H778
      Related
      ENSMMUP00000046367.2, ENSMMUT00000060118.2
      Conserved Domains (4) summary
      PHA03247
      Location:54 → 368
      PHA03247; large tegument protein UL36; Provisional
      cl07433
      Location:425 → 581
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
      pfam12026
      Location:626 → 835
      DUF3513; Domain of unknown function (DUF3513)
      cl17036
      Location:1 → 41
      SH3; Src Homology 3 domain superfamily

    5. XM_015126631.2 → XP_014982117.1  breast cancer anti-estrogen resistance protein 1 isoform X6

      UniProtKB/TrEMBL
      G7NR24
      Conserved Domains (3) summary
      cd12001
      Location:51 → 117
      SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
      pfam12026
      Location:701 → 910
      DUF3513; Domain of unknown function (DUF3513)
      cl07433
      Location:500 → 656
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

    6. XM_015126629.2 → XP_014982115.1  breast cancer anti-estrogen resistance protein 1 isoform X3

      UniProtKB/TrEMBL
      H9G270, I0FWM4
      Related
      ENSMMUP00000067662.1, ENSMMUT00000099657.1
      Conserved Domains (3) summary
      cd12001
      Location:4 → 71
      SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
      pfam12026
      Location:655 → 864
      DUF3513; Domain of unknown function (DUF3513)
      cl07433
      Location:454 → 610
      Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
    Nucleotide Protein
    Heading Accession and Version

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