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    HSCB HscB mitochondrial iron-sulfur cluster cochaperone [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713734, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HSCBprovided by VGNC
    Official Full Name
    HscB mitochondrial iron-sulfur cluster cochaperoneprovided by VGNC
    Primary source
    VGNC:VGNC:73454
    See related
    Ensembl:ENSMMUG00000020489
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HSCB in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (22789536..22804935, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (70597501..70612849)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 117 Neighboring gene X-box binding protein 1 Neighboring gene checkpoint kinase 2 Neighboring gene tetratricopeptide repeat domain 28 Neighboring gene uncharacterized LOC114670379 Neighboring gene phosphatidylinositol transfer protein beta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein complex oligomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iron-sulfur cluster co-chaperone protein HscB
    Names
    HscB iron-sulfur cluster co-chaperone homolog
    iron-sulfur cluster co-chaperone protein HscB, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194228.1 → NP_001181157.1  iron-sulfur cluster co-chaperone protein HscB

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000022
      UniProtKB/TrEMBL
      F6VJ72, G7N3I2
      Related
      ENSMMUP00000026985.4, ENSMMUT00000028837.4
      Conserved Domains (3) summary
      cd06257
      Location:72 → 131
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      PRK03578
      Location:68 → 228
      hscB; co-chaperone HscB; Provisional
      pfam07743
      Location:157 → 229
      HSCB_C; HSCB C-terminal oligomerization domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      22789536..22804935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827363.1 → XP_028683196.1  iron-sulfur cluster co-chaperone protein HscB isoform X3

      Conserved Domains (1) summary
      PRK05014
      Location:72 → 143
      hscB; co-chaperone HscB; Provisional

    2. XM_028827364.1 → XP_028683197.1  iron-sulfur cluster co-chaperone protein HscB isoform X4

      Conserved Domains (1) summary
      pfam07743
      Location:1 → 73
      HSCB_C; HSCB C-terminal oligomerization domain

    3. XM_028827365.1 → XP_028683198.1  iron-sulfur cluster co-chaperone protein HscB isoform X4

      Conserved Domains (1) summary
      pfam07743
      Location:1 → 73
      HSCB_C; HSCB C-terminal oligomerization domain

    4. XM_028827361.1 → XP_028683194.1  iron-sulfur cluster co-chaperone protein HscB isoform X2

      Conserved Domains (1) summary
      PRK05014
      Location:72 → 142
      hscB; co-chaperone HscB; Provisional

    5. XM_028827360.1 → XP_028683193.1  iron-sulfur cluster co-chaperone protein HscB isoform X1

      UniProtKB/TrEMBL
      G7N3I2
      Conserved Domains (1) summary
      PRK05014
      Location:72 → 207
      hscB; co-chaperone HscB; Provisional

    6. XM_028827362.1 → XP_028683195.1  iron-sulfur cluster co-chaperone protein HscB isoform X2

      Conserved Domains (1) summary
      PRK05014
      Location:72 → 142
      hscB; co-chaperone HscB; Provisional

    RNA

    1. XR_003719776.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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