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    ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708107, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS10provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 10provided by VGNC
    Primary source
    VGNC:VGNC:103784
    See related
    Ensembl:ENSMMUG00000016821
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS10 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (8474685..8506452, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (8730445..8762256, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 414 Neighboring gene myosin IF Neighboring gene proline-rich protein 23D1-like Neighboring gene actin like 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265632.1 → NP_001252561.1  A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor

      See identical proteins and their annotated locations for NP_001252561.1

      Status: PROVISIONAL

      Source sequence(s)
      JV565191
      UniProtKB/TrEMBL
      F7C9E9, G7NNB0, I2CU91
      Related
      ENSMMUP00000022117.4, ENSMMUT00000023636.4
      Conserved Domains (6) summary
      smart00209
      Location:550 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 454
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:239 → 457
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:73 → 179
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:706 → 818
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1069 → 1101
      PLAC; PLAC (protease and lacunin) domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      8474685..8506452 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122749.2 → XP_014978235.1  A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1

      UniProtKB/TrEMBL
      F7C9E9, G7NNB0, I2CU91
      Conserved Domains (6) summary
      smart00209
      Location:550 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 454
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:239 → 457
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:73 → 179
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:706 → 818
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1069 → 1101
      PLAC; PLAC (protease and lacunin) domain

    2. XM_028838438.1 → XP_028694271.1  A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2

      UniProtKB/TrEMBL
      G7NNB0
      Conserved Domains (6) summary
      PHA02682
      Location:856 → 994
      PHA02682; ORF080 virion core protein; Provisional
      smart00209
      Location:550 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 454
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:695 → 807
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam01562
      Location:40 → 180
      Pep_M12B_propep; Reprolysin family propeptide
      pfam08686
      Location:1058 → 1090
      PLAC; PLAC (protease and lacunin) domain

    3. XM_015122751.2 → XP_014978237.1  A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3

      Conserved Domains (3) summary
      smart00209
      Location:497 → 541
      TSP1; Thrombospondin type 1 repeats
      pfam05986
      Location:193 → 305
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:556 → 588
      PLAC; PLAC (protease and lacunin) domain

    4. XM_015122750.2 → XP_014978236.1  A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1

      UniProtKB/TrEMBL
      F7C9E9, G7NNB0, I2CU91
      Conserved Domains (6) summary
      smart00209
      Location:550 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 454
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:239 → 457
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:73 → 179
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:706 → 818
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1069 → 1101
      PLAC; PLAC (protease and lacunin) domain

    RNA

    1. XR_001441244.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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