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    MCM6 minichromosome maintenance complex component 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707651, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MCM6provided by VGNC
    Official Full Name
    minichromosome maintenance complex component 6provided by VGNC
    Primary source
    VGNC:VGNC:74685
    Locus tag
    EGK_05717
    See related
    Ensembl:ENSMMUG00000017486
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MCM6 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (21000735..21038175, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (21342638..21380508, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671317 Neighboring gene UBX domain protein 4 Neighboring gene lactase Neighboring gene glycoprotein endo-alpha-1,2-mannosidase-like protein pseudogene Neighboring gene aspartyl-tRNA synthetase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA unwinding involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via break-induced replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MCM complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication licensing factor MCM6
    NP_001247544.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260615.1 → NP_001247544.1  DNA replication licensing factor MCM6

      See identical proteins and their annotated locations for NP_001247544.1

      Status: PROVISIONAL

      Source sequence(s)
      JU320155
      UniProtKB/TrEMBL
      A0A1D5R126, A0A8J8XNM7, F6VC72, G7NB01
      Related
      ENSMMUP00000023011.4, ENSMMUT00000024584.4
      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      21000735..21038175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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