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    CAPN13 calpain 13 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706966, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CAPN13provided by VGNC
    Official Full Name
    calpain 13provided by VGNC
    Primary source
    VGNC:VGNC:70571
    See related
    Ensembl:ENSMMUG00000003473
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CAPN13 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (78074312..78185512)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (31133054..31245649, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992891 Neighboring gene uncharacterized LOC114671741 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 14 Neighboring gene uncharacterized LOC106992890 Neighboring gene lysocardiolipin acyltransferase 1 Neighboring gene LBH regulator of WNT signaling pathway

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      78074312..78185512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112043.2 → XP_014967529.2  calpain-13

      UniProtKB/TrEMBL
      F7EBC1, G7N9R9
      Related
      ENSMMUP00000004631.4, ENSMMUT00000004916.4
      Conserved Domains (3) summary
      cd16195
      Location:501 → 669
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:35 → 331
      Peptidase_C2; Calpain family cysteine protease
      cl00165
      Location:359 → 474
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    2. XM_015112042.2 → XP_014967528.2  calpain-13

      UniProtKB/TrEMBL
      F7EBC1, G7N9R9
      Conserved Domains (3) summary
      cd16195
      Location:501 → 669
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:35 → 331
      Peptidase_C2; Calpain family cysteine protease
      cl00165
      Location:359 → 474
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    3. XM_028831804.1 → XP_028687637.1  calpain-13

      UniProtKB/TrEMBL
      F7EBC1, G7N9R9
      Conserved Domains (3) summary
      cd16195
      Location:501 → 669
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:35 → 331
      Peptidase_C2; Calpain family cysteine protease
      cl00165
      Location:359 → 474
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    RNA

    1. XR_001438997.2 RNA Sequence

    2. XR_003721800.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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