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    PCF11 PCF11 cleavage and polyadenylation factor subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704490, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PCF11provided by VGNC
    Official Full Name
    PCF11 cleavage and polyadenylation factor subunitprovided by VGNC
    Primary source
    VGNC:VGNC:75701
    See related
    Ensembl:ENSMMUG00000005029
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PCF11 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (76305720..76334860)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (75523463..75552557)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene RAB30, member RAS oncogene family Neighboring gene uncharacterized LOC114672366 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene uncharacterized LOC106993409 Neighboring gene uncharacterized LOC106993411 Neighboring gene cyclin-dependent kinases regulatory subunit 1 pseudogene Neighboring gene ankyrin repeat domain 42

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in termination of RNA polymerase II transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of mRNA cleavage factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA cleavage complex 2 protein Pcf11
    Names
    pre-mRNA cleavage complex 2 protein Pcf11-like
    pre-mRNA cleavage complex II protein Pcf11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      76305720..76334860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115346.2 → XP_014970832.1  pre-mRNA cleavage complex 2 protein Pcf11 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZM27
      Related
      ENSMMUP00000066682.1, ENSMMUT00000103123.1
      Conserved Domains (2) summary
      pfam01391
      Location:1153 → 1222
      Collagen; Collagen triple helix repeat (20 copies)
      cd03562
      Location:19 → 130
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...

    2. XM_015115344.2 → XP_014970830.1  pre-mRNA cleavage complex 2 protein Pcf11 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZM27
      Conserved Domains (2) summary
      pfam01391
      Location:1153 → 1222
      Collagen; Collagen triple helix repeat (20 copies)
      cd03562
      Location:19 → 130
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...

    3. XM_015115347.2 → XP_014970833.1  pre-mRNA cleavage complex 2 protein Pcf11 isoform X3

      UniProtKB/TrEMBL
      F7ASL5, G7NEG2, H9FVM7
      Related
      ENSMMUP00000006658.4, ENSMMUT00000007086.4
      Conserved Domains (1) summary
      cd03562
      Location:19 → 130
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...

    4. XM_028833877.1 → XP_028689710.1  pre-mRNA cleavage complex 2 protein Pcf11 isoform X4

      UniProtKB/TrEMBL
      G7NEG2
      Conserved Domains (4) summary
      TIGR00618
      Location:195 → 445
      sbcc; exonuclease SbcC
      PTZ00108
      Location:374 → 616
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      pfam09606
      Location:858 → 1266
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd16982
      Location:19 → 145
      CID_Pcf11; CID (CTD-Interacting Domain) of Pcf11
    Nucleotide Protein
    Heading Accession and Version

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