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    SCN3A sodium voltage-gated channel alpha subunit 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703178, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SCN3Aprovided by VGNC
    Official Full Name
    sodium voltage-gated channel alpha subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:76985
    See related
    Ensembl:ENSMMUG00000018840
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SCN3A in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (52235997..52351711, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (52006487..52122365, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 38 member 11 Neighboring gene uncharacterized LOC106992600 Neighboring gene microtubule-associated protein RP/EB family member 1 pseudogene Neighboring gene sodium voltage-gated channel alpha subunit 2 Neighboring gene cysteine and serine rich nuclear protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 3 subunit alpha
    Names
    sodium channel, voltage-gated, type III, alpha subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      52235997..52351711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830785.1 → XP_028686618.1  sodium channel protein type 3 subunit alpha isoform X4

      UniProtKB/TrEMBL
      F6VIY2
      Conserved Domains (5) summary
      cd13433
      Location:1423 → 1475
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1159 → 1431
      Ion_trans; Ion transport protein
      pfam06512
      Location:952 → 1154
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 664
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1747 → 1794
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    2. XM_015110273.2 → XP_014965759.2  sodium channel protein type 3 subunit alpha isoform X3

      UniProtKB/TrEMBL
      F6VIY2
      Conserved Domains (5) summary
      cd13433
      Location:1452 → 1504
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1188 → 1460
      Ion_trans; Ion transport protein
      pfam06512
      Location:981 → 1183
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 693
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1776 → 1823
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    3. XM_015110270.2 → XP_014965756.2  sodium channel protein type 3 subunit alpha isoform X1

      UniProtKB/TrEMBL
      F6VIY2, F6ZAM3
      Conserved Domains (5) summary
      cd13433
      Location:1469 → 1521
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1205 → 1477
      Ion_trans; Ion transport protein
      pfam06512
      Location:998 → 1200
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 710
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1793 → 1840
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    4. XM_028830786.1 → XP_028686619.1  sodium channel protein type 3 subunit alpha isoform X7

      Conserved Domains (6) summary
      cd13433
      Location:839 → 891
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam07989
      Location:1267 → 1308
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam00520
      Location:575 → 847
      Ion_trans; Ion transport protein
      pfam06512
      Location:368 → 570
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:45 → 70
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1155 → 1218
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    5. XM_015110274.2 → XP_014965760.2  sodium channel protein type 3 subunit alpha isoform X5

      UniProtKB/TrEMBL
      F6VIY2
      Conserved Domains (5) summary
      cd13433
      Location:1420 → 1472
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1156 → 1428
      Ion_trans; Ion transport protein
      pfam06512
      Location:949 → 1151
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 661
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1744 → 1791
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    6. XM_015110275.2 → XP_014965761.2  sodium channel protein type 3 subunit alpha isoform X6

      UniProtKB/TrEMBL
      F6VIY2
      Conserved Domains (5) summary
      cd13433
      Location:1420 → 1472
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1156 → 1428
      Ion_trans; Ion transport protein
      pfam06512
      Location:949 → 1151
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 661
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1744 → 1791
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    7. XM_015110271.2 → XP_014965757.2  sodium channel protein type 3 subunit alpha isoform X2

      UniProtKB/TrEMBL
      F6VIY2
      Related
      ENSMMUP00000011026.4, ENSMMUT00000011757.4
      Conserved Domains (5) summary
      cd13433
      Location:1469 → 1521
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1205 → 1477
      Ion_trans; Ion transport protein
      pfam06512
      Location:998 → 1200
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 710
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1793 → 1840
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    8. XM_015110272.2 → XP_014965758.2  sodium channel protein type 3 subunit alpha isoform X1

      UniProtKB/TrEMBL
      F6VIY2, F6ZAM3
      Related
      ENSMMUP00000024797.4, ENSMMUT00000026493.4
      Conserved Domains (5) summary
      cd13433
      Location:1469 → 1521
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1205 → 1477
      Ion_trans; Ion transport protein
      pfam06512
      Location:998 → 1200
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:513 → 710
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1793 → 1840
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
    Heading Accession and Version

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