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    PLK1 polo like kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697686, updated on 5-Mar-2024

    Summary

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    Gene symbol
    PLK1
    Gene description
    polo like kinase 1
    Locus tag
    EGK_12605
    See related
    Ensembl:ENSMMUG00000017306
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLK1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (22010899..22034975)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (22371132..22394672)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1 Neighboring gene partner and localizer of BRCA2 Neighboring gene dynactin subunit 5 Neighboring gene endoplasmic reticulum to nucleus signaling 2 Neighboring gene calcineurin like EF-hand protein 2 Neighboring gene protein kinase C beta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PLK1
    Names
    Serine/threonine-protein kinase PLK1
    XP_001092070.1
    XP_014981288.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      22010899..22034975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015125802.2 → XP_014981288.1  serine/threonine-protein kinase PLK1

      UniProtKB/TrEMBL
      A0A8J8XQA8, F7HSC1, G7NQ18, H9ZA67
      Related
      ENSMMUP00000022766.2, ENSMMUT00000024323.4
      Conserved Domains (3) summary
      cd13117
      Location:509 → 590
      POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd13118
      Location:407 → 494
      POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd14187
      Location:45 → 309
      STKc_PLK1; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 1

    2. XM_001092070.4 → XP_001092070.1  serine/threonine-protein kinase PLK1

      See identical proteins and their annotated locations for XP_001092070.1

      UniProtKB/TrEMBL
      A0A8J8XQA8, F7HSC1, G7NQ18, H9ZA67
      Conserved Domains (3) summary
      cd13117
      Location:509 → 590
      POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd13118
      Location:407 → 494
      POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd14187
      Location:45 → 309
      STKc_PLK1; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 1
    Nucleotide Protein
    Heading Accession and Version

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