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    UBA3 ubiquitin like modifier activating enzyme 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696493, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UBA3provided by VGNC
    Official Full Name
    ubiquitin like modifier activating enzyme 3provided by VGNC
    Primary source
    VGNC:VGNC:78689
    See related
    Ensembl:ENSMMUG00000008620
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See UBA3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (125200163..125225679, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (72842726..72868697)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene EGF domain specific O-linked N-acetylglucosamine transferase Neighboring gene TATA element modulatory factor 1 Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 5 Neighboring gene leiomodin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NEDD8 activating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein neddylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NEDD8-activating enzyme E1 catalytic subunit
    NP_001252890.1
    XP_014985886.1
    XP_014985887.1
    XP_014985888.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265961.1 → NP_001252890.1  NEDD8-activating enzyme E1 catalytic subunit

      See identical proteins and their annotated locations for NP_001252890.1

      Status: PROVISIONAL

      Source sequence(s)
      JU470540
      UniProtKB/TrEMBL
      A0A1D5QI64, H9YUH8
      Related
      ENSMMUP00000070522.1, ENSMMUT00000097885.1
      Conserved Domains (2) summary
      cd01488
      Location:71 → 368
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam08825
      Location:376 → 461
      E2_bind; E2 binding domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      125200163..125225679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130401.2 → XP_014985887.1  NEDD8-activating enzyme E1 catalytic subunit isoform X2

      UniProtKB/TrEMBL
      A0A1D5QI64, F7FCV8
      Related
      ENSMMUP00000011312.4, ENSMMUT00000012059.4
      Conserved Domains (2) summary
      cd01488
      Location:62 → 341
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam08825
      Location:349 → 434
      E2_bind; E2 binding domain

    2. XM_015130402.2 → XP_014985888.1  NEDD8-activating enzyme E1 catalytic subunit isoform X3

      UniProtKB/TrEMBL
      A0A1D5QI64
      Conserved Domains (2) summary
      cd01488
      Location:48 → 327
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam08825
      Location:335 → 420
      E2_bind; E2 binding domain

    3. XM_015130400.2 → XP_014985886.1  NEDD8-activating enzyme E1 catalytic subunit isoform X1

      UniProtKB/TrEMBL
      A0A1D5QI64, F7FCV2, H9FCH7
      Related
      ENSMMUP00000011313.4, ENSMMUT00000012060.4
      Conserved Domains (2) summary
      cd01488
      Location:57 → 354
      Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam08825
      Location:362 → 447
      E2_bind; E2 binding domain
    Nucleotide Protein
    Heading Accession and Version

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