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    DSTN destrin, actin depolymerizing factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695969, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DSTNprovided by VGNC
    Official Full Name
    destrin, actin depolymerizing factorprovided by VGNC
    Primary source
    VGNC:VGNC:71841
    See related
    Ensembl:ENSMMUG00000013786
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DSTN in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (48892519..48927876, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (50744498..50779166)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene BANF family member 2 Neighboring gene ribosome binding protein 1 Neighboring gene uncharacterized LOC107000481 Neighboring gene beaded filament structural protein 1 Neighboring gene ubiquitin-40S ribosomal protein S27a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament fragmentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    destrin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195492.1 → NP_001182421.1  destrin

      See identical proteins and their annotated locations for NP_001182421.1

      Status: VALIDATED

      Source sequence(s)
      CO649015, DV769372, DV769930
      UniProtKB/TrEMBL
      A0A1D5QKS7, F6TEG7, G7N310, H9EM17
      Related
      ENSMMUP00000080833.1, ENSMMUT00000093699.1
      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      48892519..48927876 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827175.1 → XP_028683008.1  destrin isoform X1

      UniProtKB/TrEMBL
      G7N310
      Conserved Domains (1) summary
      smart00102
      Location:2 → 136
      ADF; Actin depolymerisation factor/cofilin -like domains
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.