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    MYC MYC proto-oncogene, bHLH transcription factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694626, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYCprovided by VGNC
    Official Full Name
    MYC proto-oncogene, bHLH transcription factorprovided by VGNC
    Primary source
    VGNC:VGNC:109507
    Locus tag
    EGK_19271
    See related
    Ensembl:ENSMMUG00000014601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    c-Myc
    Orthologs
    human mouse all
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    Genomic context

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    See MYC in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (128098629..128104634)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (127089827..127095160)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114680332 Neighboring gene uncharacterized LOC114680333 Neighboring gene uncharacterized LOC106999943 Neighboring gene U1 spliceosomal RNA Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Liu H, et al. Cell Stem Cell, 2008 Dec 4. PMID 19041774
    2. An empirical test for branch-specific positive selection. Nickel GC, et al. Genetics, 2008 Aug. PMID 18689901, Free PMC Article
    3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myc proto-oncogene protein
    Names
    proto-oncogene c-Myc
    transcription factor p64
    v-myc avian myelocytomatosis viral oncogene homolog
    v-myc myelocytomatosis viral oncogene homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142873.1 → NP_001136345.1  myc proto-oncogene protein

      See identical proteins and their annotated locations for NP_001136345.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ375753
      UniProtKB/Swiss-Prot
      B8XIA5, H9Z974
      UniProtKB/TrEMBL
      G7N040
      Conserved Domains (2) summary
      cd11458
      Location:351 → 434
      bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
      pfam01056
      Location:6 → 345
      Myc_N; Myc amino-terminal region

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      128098629..128104634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028852119.1 → XP_028707952.1  myc proto-oncogene protein isoform X1

      UniProtKB/Swiss-Prot
      B8XIA5, H9Z974
      UniProtKB/TrEMBL
      G7N040
      Conserved Domains (2) summary
      cd11458
      Location:351 → 434
      bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
      pfam01056
      Location:6 → 345
      Myc_N; Myc amino-terminal region

    2. XM_015145930.1 → XP_015001416.1  myc proto-oncogene protein isoform X1

      UniProtKB/Swiss-Prot
      B8XIA5, H9Z974
      UniProtKB/TrEMBL
      G7N040
      Related
      ENSMMUP00000056069.2, ENSMMUT00000058254.2
      Conserved Domains (2) summary
      cd11458
      Location:351 → 434
      bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
      pfam01056
      Location:6 → 345
      Myc_N; Myc amino-terminal region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B8XIA5.2 GenPept UniProtKB/Swiss-Prot:B8XIA5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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